“I am proud of our seroprevalence calculator, which (for example) calculates the true sero-prevalence of antibodies to SARS-CoV-2 based on a study that uses an imperfect antibody test. (The website team calls this the "seroprevalence" calculator as a short-hand, since it's immediately relevant to current COVID-19 seroprevalence studies.) It runs the calculations in two different ways, according to two slightly different mathematical models. The site also has additional calculators that will be useful to individuals studying and using diagnostic tests (e.g., for COVID-19) such as this one, which estimates the true prevalence of disease in the population: The standard calculators help investigators determine:ġ) the precision with which they can estimate a parameter given their sample size,Ģ) the sample size that they need to estimate a parameter with a certain precision,ģ) the minimum detectable effect size given group sizes, andĤ) the required group sizes given the minimum detectable effect size. Kohn worked with site co-developer Josh Senyak on the site redesign. "Josh and I have added many new calculators, a tool to help you find the right calculator, and a summary page that shows all the calculators on the site,” Kohn said. We have added many new calculators, a tool to help you find the right calculator, and a summary page that shows all the calculators on the site,” said Michael Kohn, MD, MPP, member of CTSI’s Study Design consultation unit (part of the Consultation Services program) and the Sample-Size website, and professor of Epidemiology and Biostatistics. “The site redesign should make it even more useful to clinical researchers. The website has recently gone through a redesign with added improvements based on user feedback as well as new calculators to help researchers. It is the standard site used for UCSF courses, including Designing Clinical Research and the undergraduate medical education courses on Epidemiology, Biostatistics, and Population Science (EBPS). Body mass index (BMI) is a measure of body fat based on height and weight that applies to adult men and women. Since its launch in 2017, the Clinical and Translational Science Institute’s Sample Size calculator website ( ) has gained traction not only at UCSF, but nationwide – it had 300,000 sessions in the past year with users from 1,200+ universities. Screenshot of a typical calculator page (Source: ) Funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health (NIH), the Network is a collaboration between NICUs from academic medical centers across the US and a coordinating center.
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